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linkedin.com
#phdlife #drugdelivery #sirna | School of Pharmacy, UCC
Research led by PhD candidate Michael Neary has been published in the European Journal of Pharmaceutical Sciences. This work describes the application of nebulisation for pulmonary delivery of lipid-based siRNA nanocarriers. Using both laser diffraction and cascade impaction analysis, they demonstrated the potential of siRNA lipoplexes and ...
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1 month ago
Small interfering RNA siRNA Therapy
1:02
Cells use messenger RNA (mRNA) to carry instructions from DNA to make proteins. Sometimes, unwanted proteins can cause or contribute to disease. RNAi therapeutics disrupt this process by targeting specific mRNA molecules and preventing the production of disease-associated proteins. This video explains how RNAi therapeutics use small interfering RNA (siRNA) and a naturally occurring protein complex in the body to intercept and degrade target mRNA before harmful proteins can be made. Learn more ab
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2.4K views · 94 reactions | Higher circulating lipoprotein(a) concentrations are associated with atherosclerotic cardiovascular disease. Olpasiran is a small interfering RNA molecule that reduces LP(a). New research findings are summarized in a short video. https://nej.md/3UK1KgE | The New England Journal of Medicine | Facebook
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