🩸 Tranexamic Acid (TXA) – How does it actually work? When trauma patients bleed, their body forms clots to stop the loss. But the body also activates fibrinolysis – the natural breakdown of clots. In major haemorrhage this can become overactive, leading to clot breakdown before bleeding is controlled. 👉 TXA works by blocking plasminogen from converting into plasmin, the enzyme that dissolves fibrin clots. 👉 This helps stabilise clots, reduce bleeding, and improve survival if given within 3 ho
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🩸 Tranexamic Acid (TXA) – How does it actually work? When trauma pat…
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How Tranexamic Acid (TXA) Stops Bleeding: The Mechanism of Action
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How Tranexamic Acid (TXA) Stops Bleeding: The Mechanism of Action
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To minimize bruising after surgery, we start early: epinephrine in the local anesthetic reduces bleeding, and TXA (tranexamic acid) in the IV helps limit bruising during the procedure. After surgery, immediate cold compresses and gentle pressure are key to calming the clotting process and keeping bruising to a minimum. | Dr David B Samimi, Eyesthetica
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