USMLE High-Yield Questions on Instagram: "“tolerance kicked in but some things never change” ⸻ 📚 EXPLANATION (WITH ANSWER) Future’s been drinking lean for years, meaning chronic opioid use. With long-term opioid exposure, the body develops tolerance to many effects — but not all. Opioid effects that DO develop tolerance: • Euphoria • Analgesia • Respiratory depression • Sedation • Nausea Opioid effects that DO NOT develop tolerance: • Constipation → μ-receptor activation in the GI tract ↓ peris
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USMLE High-Yield Questions on Instagram: "“tolerance kicked in but some things never change” ⸻ 📚 EXPLANATION (WITH ANSWER) Future’s been drinking lean for years,
Learn how to identify the opioid effects that persist despite tolerance and why they remain a concern for medical professionals and students. Get expert advice on high-yield pharmacology topics and improve your USMLE preparation.
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