Objectives Acute anterior ischaemic optic neuropathy (AION) is a feared ischaemic complication of giant cell arteritis (GCA).

Objectives Anti-neutrophil cytoplasmic antibody-associated vasculitis (AAV) is a systemic autoimmune disease where infections ...

Takayasu arteritis (TAK) remains a therapeutic challenge, and some patients develop refractory disease despite conventional ...

is an open access, peer-reviewed rheumatology journal that publishes original research on rheumatic and musculoskeletal disorders and connective tissue diseases ...

Introduction Patients with rheumatoid (RA) or psoriatic (PsA) arthritis can experience debilitating pain. Methods Post hoc analyses of phase 3, double-blind studies in patients with active disease ...

Objectives We aimed to develop a new complex intervention, the ‘COuld it Be RA’ (COBRA) tool, to support the implementation of a clinical prediction model to identify people likely to be anti-cyclic ...

Background The aim of this systematic review and meta-analysis was to examine autoantibody positive individuals and define: (a) the relative risk of rheumatoid arthritis (RA) compared with ...

Introduction Familial Mediterranean fever (FMF) is the most common monogenic autoinflammatory disease. Colchicine is the first-line treatment, yet 5–10% of patients are resistant, increasing the risk ...

Real-world data are increasingly available to investigate ‘real-world’ safety and efficacy. However, since treatment in observational studies is not randomly allocated, confounding by indication may ...

Objective To assess the prevalence of frailty in rheumatoid arthritis (RA) and its association with baseline and longitudinal disease activity, all-cause mortality and hospitalisation. Participants ...

Objective Studies of dermatomyositis (DM) are frequently limited to single-centre cohorts. We used two large nationally representative US cohorts to conduct a descriptive epidemiological study of the ...