Drug metabolism is a central factor in drug discovery and development, impacting safety, pharmacokinetics, and pharmacodynamics. Research into drugs’ in vitro metabolism in human and animal tissues ...

Information is power and never more so than in the world of drug development. For a pharmaceutical company, having detailed knowledge of how a drug candidate is metabolized as early as possible in the ...

This episode of the Pharmaron DMPK Insights Podcast Series sees Dan Weston (Scientific Leader of Biotransformation at GSK) provide insight into his recent publication on the importance of Metabolite ...

In this short, information-packed ADME 101 video, one of the principal scientists in our program oversight department discusses the main frequently asked questions that we receive about metabolite ...

Sapient, a leading biomarker discovery organization providing at scale services for multi-omics data generation and analysis, announced today a major advancement in their mass spectrometry-based ...

Overall, specific lipids and amino acids were indicated as the most common metabolite classes associated with breast cancer development. However, comparison of results across studies is challenging ...

Can you describe how the untargeted ultrahigh-performance liquid chromatography–high resolution tandem mass spectrometry (UHPLC–HRMS/MS) workflow was designed to capture both known salicylates and ...