Since the 1950s a chemotherapy drug known as 5-fluorouracil (5-FU) has been used to treat many types of cancer, including blood cancers and cancers of the digestive tract. Doctors have long believed ...

Doctors have long believed the cancer drug 5-fluorouracil works by damaging the building blocks of DNA, but researchers have now found that in certain cancers, it kills cells by interfering with RNA ...

A new case report was published in Volume 12 of Oncoscience on December 23, 2025, titled “Silent toxicity: A rare case of 5-fluorouracil-induced hyperammonemic encephalopathy.” ...

The comparative efficacy of surgical excision, 5-fluorouracil, and methylaminolevulinate photodynamic therapy for the treatment of Bowen disease was examined.

Omitting bolus 5-fluorouracil (5-FU) from combination chemotherapy for gastrointestinal (GI) cancers did not adversely affect survival and was associated with less toxicity, a review of a large ...

Study reveals the drug, 5-fluorouracil, acts differently in different types of cancer — a finding that could help researchers design better drug combinations. Since the 1950s, a chemotherapy drug ...

The FDA highlights increased toxicity risks in patients with DPD deficiency when using Xeloda and 5-FU, urging genetic testing before treatment. DPD deficiency leads to severe side effects from ...