pharmaphorum

BARDA backs Locus phage therapy for resistant E coli

The US government has provided almost $24 million in funding to Locus Biosciences to support a mid-stage trial of LBP-EC01, a CRISPR-engineered bacteriophage therapy in development for resistant ...
IEEE

Arc-Support Line Segments Revisited: An Efficient High-Quality Ellipse Detection

Abstract: Over the years many ellipse detection algorithms spring up and are studied broadly, while the critical issue of detecting ellipses accurately and efficiently in real-world images remains a ...
IEEE

LOCUS: learning object classes with unsupervised segmentation

Abstract: We address the problem of learning object class models and object segmentations from unannotated images. We introduce LOCUS (learning object classes with unsupervised segmentation) which ...
eLife

Descending locus coeruleus noradrenergic signaling to spinal astrocyte subset is required for stress-induced mechanical pain hypersensitivity

This important study identifies a novel role for Hes5+ astrocytes in modulating the activity of descending pain-inhibitory noradrenergic neurons from the locus coeruleus during stress-induced pain ...