The remote control doesn’t trigger the self-destruction of the CAR T cells, but simply prompts them to disengage from their cancerous targets.

Bacteria in the gut may influence how GLP-1 receptor agonists work. This could help explain why patients do not respond ...

Among the most promising tools of cancer therapy, engineered immune cells known as chimeric antigen-receptor (CAR) T cells have already transformed the treatment of blood cancers. Yet, despite their ...

Researchers have discovered that drugs like Ozempic for diabetes and obesity also improve alcohol use disorders and other ...

HCB101, a novel Fc-based anti-SIRPα-CD47 fusion protein, has received orphan drug designation (ODD) from the FDA for the ...

G-protein-coupled receptors (GPCRs) are one of the biggest groups of cell surface proteins in the human body, recognizing hormones, neurotransmitters, and drugs.

G-protein-coupled receptors (GPCRs) are one of the largest families of cell surface proteins in the human body that recognize hormones, neurotransmitters, and drugs. These receptors regulate a wide ...

Researchers find that a common glaucoma drug, acetazolamide, can reverse brain changes and prevent relapse in opioid use disorder.

G-protein-coupled receptors (GPCRs) are one of the largest families of cell surface proteins in the human body that recognize hormones, neurotransmitters, and drugs.

New approaches to obesity treatment are emerging as scientists target underexplored metabolic pathways with the help of artificial intelligence. Demand for better obesity medicines is rising quickly, ...

Understanding the thermodynamic basis of ligand recognition by G-protein-coupled receptors (GPCRs), especially in terms of ...

An existing drug currently used to treat glaucoma, altitude sickness, and seizures may also have the potential to prevent ...