Understanding the thermodynamic basis of ligand recognition by G-protein-coupled receptors (GPCRs), especially in terms of ...
G-protein-coupled receptors (GPCRs) are one of the largest families of cell surface proteins in the human body that recognize hormones, neurotransmitters, and drugs. These receptors regulate a wide ...
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Thermodynamic insights into histamine H1 receptor ligand binding
G-protein-coupled receptors (GPCRs) are one of the largest families of cell surface proteins in the human body that recognize hormones, neurotransmitters, and drugs. These receptors regulate a wide ...
The remote control doesn’t trigger the self-destruction of the CAR T cells, but simply prompts them to disengage from their cancerous targets.
Madrigal has made three in-licensing deals since July 2025, picking up multiple potential MASH therapeutics. Read why MDGL ...
An existing drug currently used to treat glaucoma, altitude sickness, and seizures may also have the potential to prevent ...
Researchers report that acetazolamide prevented adverse brain changes caused by cocaine withdrawal in mice, suggesting the approved drug could be repurposed to target relapse-related pathways.
A retrospective study sought to confirm real-world outcomes of patients with HER2+ breast cancer treated with trastuzumab deruxtecan.
New approaches to obesity treatment are emerging as scientists target underexplored metabolic pathways with the help of artificial intelligence. Demand for better obesity medicines is rising quickly, ...
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