The superfamily of proteins called cytochrome P450 (CYP) enzymes are involved in the synthesis and metabolism of a range of internal and external cellular components. These enzymes have been ...
Cytochrome P450 enzymes constitute a superfamily of haem-containing proteins that catalyse the oxidation of a wide range of exogenous and endogenous compounds. Their function is fundamental to the ...
The first-ever structure of a full-length P450 enzyme has been solved. Cells use these enzymes to synthesize hormones and metabolize drugs. Chemists would like to engineer them to carry out reactions ...