RNA therapeutics target translation rather than DNA, aiming to correct shared protein production errors. By enabling cells to read through premature stop codons, engineered tRNAs could restore ...
With big pharma signalling interest in novel RNA-targeted approaches, the term “druggable” is being redefined as technology advances.
Researchers develop a single genome-editing strategy to treat multiple disorders caused by nonsense mutations, promising efficient and cost-effective therapies.
*A.P.: contact about chemical aspects and supramolecular interactions. Tel.: +39 091 23897543. Fax: +39 091 596825. E-mail: [email protected] *A.D.L.: contact about ...
A new paper from the laboratory of David Liu, PhD, at the Broad Institute describes a genome-editing strategy that could result in a one-time treatment for multiple unrelated genetic diseases. The new ...
In people with CF, the gene encoding a protein called the cystic fibrosis transmembrane conductance regulator (CFTR) is faulty. This especially affects the airways, causing the airway surface to dry ...
To overcome the inherent challenge of translation termination interference caused by stop codon reprogramming in mammalian cells, researchers from Peking University led by Chen Peng from College of ...
Wrongful termination includes being fired for discriminatory reasons, violations of the FMLA or as retaliation for legal complaints. Key federal laws such as the Civil Rights Act, ADA, ADEA and PDA ...
The Federal Communications Commission voted to ban cable and satellite companies from charging early termination fees. The rule, introduced in November, will also require companies to issue a prorated ...
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