Astrocytes use the MEGF10 receptor to prune synapses in the striatum, a process essential for dopamine-driven motor learning.

Surgery in UC Hospital operating room, 1924. This photograph from 1924, taken in one of the operating rooms at the University of California Hospital (present day UCSF), is spare and almost austere.

When we learn a new motor skill—whether mastering a piano passage or refining balance while walking—the brain must reorganize the circuits that control movement. For decades, this process of synaptic ...