Since the 1950s a chemotherapy drug known as 5-fluorouracil (5-FU) has been used to treat many types of cancer, including blood cancers and cancers of the digestive tract. Doctors have long believed ...

Doctors have long believed the cancer drug 5-fluorouracil works by damaging the building blocks of DNA, but researchers have now found that in certain cancers, it kills cells by interfering with RNA ...

The comparative efficacy of surgical excision, 5-fluorouracil, and methylaminolevulinate photodynamic therapy for the treatment of Bowen disease was examined.

Study reveals the drug, 5-fluorouracil, acts differently in different types of cancer — a finding that could help researchers design better drug combinations. Since the 1950s, a chemotherapy drug ...

Omitting bolus 5-fluorouracil (5-FU) from combination chemotherapy for gastrointestinal (GI) cancers did not adversely affect survival and was associated with less toxicity, a review of a large ...

The FDA highlights increased toxicity risks in patients with DPD deficiency when using Xeloda and 5-FU, urging genetic testing before treatment. DPD deficiency leads to severe side effects from ...