MDR3 defects are involved in the development of PFIC3, LPAC, ICP, and DILI. Sterolin 1/2 are cotransporters that transport plant sterols and can lead to sitosterolemia if mutated. MRP2 is responsible ...
Integrated analysis of pivotal biomarker, immune cell infiltration, and therapeutic drugs for LSM1-mutated in breast cancer. This is an ASCO Meeting Abstract from the 2022 ASCO Annual Meeting I. This ...
A new editorial paper titled "Targeting ABC transporters in PDAC—past, present, or future?" has been published in Oncotarget. Science X Daily and the Weekly Email Newsletter are free features that ...
Fecal metabolome and microflora differences between colorectal cancer patients and healthy adults. This is an ASCO Meeting Abstract from the 2013 ASCO Annual Meeting I. This abstract does not include ...
Tamoxifen reduces the rate of breast cancer recurrence by approximately a half. Tamoxifen is metabolized to more active metabolites by enzymes encoded by polymorphic genes, including cytochrome P450 ...
Using cryo-EM structure determination, molecular dynamics simulations, and electrophysiological analyses, researchers from the Shanghai Institute of Materia Medica of the Chinese Academy of Sciences ...
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