The length of telomeres that protect the ends of our chromosomes should be tightly regulated. Those that are too long predispose to cancer, and those that are too short lose their protective ability, ...
The length of telomeres that protect the ends of our chromosomes should be tightly regulated. Those that are too long predispose to cancer, and those that are too short lose their protective ability, ...
Longer leukocyte telomere length is associated with higher left ventricular mass (LVM) and larger global ventricular size, as well as better cardiac function and lower risk of heart failure (HF). The ...
Heritable pathogenic defects in genes related to mitosis and telomere function may specifically increase the risk for sarcomas – rare cancers that develop in muscles, bones, and other connective ...
As we age, our appearance changes, our hair turns gray and wrinkles appear. And we become more susceptible to disease. One reason for this is that our telomeres shorten. These are protective caps at ...
Much the way the caps on the ends of a shoelace prevent it from fraying, telomeres - regions of repetitive DNA sequences and a protein structure - protect the tips of chromosomes from damage. Every ...
In Lewis Carroll's "Through the Looking-Glass," Alice is stuck in a never-ending race with the Red Queen yet never gains a ...
New findings describe how the enzyme CST is recruited to the end of the telomere, where it maintains telomere length with the help of subtle chemical changes made to the protein POT1. The length of ...
CST (purple/lavender) bound to POT1 (red). Phosphorylation of the crimson-highlighted region in POT1 regulates the recruitment and activity of CST–Polα-primase at telomeres. The length of telomeres ...
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