The peptide commonly referred to as SNAP-8 (acetyl octapeptide-3) is a synthetic fragment derivative of SNAP-25, engineered to modulate the SNARE complex and potentially support neurotransmitter ...
The chaperone Hsc70 (green) helps keep SNAP-25 in the proper shape so that it can help form the SNARE complex, enabling neurotransmission. AMHERST, Mass. – A team of researchers from the University of ...
When cells utilize glucose as a carbon source, the HBP functions normally, maintaining intracellular O-GlcNAcylation at a high level. In this state, O-GlcNAc-modified SNAP25 stabilizes its interaction ...
For this article, Eugene Russo interviewed Axel T. Brunger, a Howard Hughes Medical Institute investigator and professor of molecular and cellular physiology at Stanford University. Data from the Web ...