Scientists identify a "master regulator" that may reset Brain Aging by controlling tau and gene expression in neurons.

A research team led by Zhiping Weng, Ph.D., and Jill Moore, Ph.D."18, at UMass Chan Medical School, has nearly tripled the ...

Citrullination, a transformative protein post-translational modification, is gaining recognition for its wide-ranging impact on cellular function and human disease. This process, driven by the enzyme ...

Immune checkpoint inhibitors (ICIs) have revolutionized cancer therapy by harnessing the body's immune system to target tumors. Despite their initial clinical success, many patients eventually ...

In modern functional genomics, understanding how specific genes control cellular behavior requires both targeted intervention and high-resolution analysis. That’s where Perturb-Seq comes in—a method ...

A comprehensive encyclopedia of the known functions of all protein-coding human genes has just been completed and released. Researchers used large-scale evolutionary modeling to integrate data on ...

Triterpenoid saponins are widely valued for their diverse pharmacological activities and also play important defensive roles ...

Every cell in our body starts out with the same set of genetic instructions, or DNA. Yet only some of these genes are expressed in each cell, leading to the production of proteins that perform the ...

Could a gene regulatory network in gut microbes have evolved its elaborate and tightly regulated molecular machinery only to pump out antibiotics indiscriminately? Researchers from the Institute of ...

Researchers developed theoretical foundations for methods that could identify the best way to aggregate genes into modules and efficiently learn the underlying cause-and-effect relationships among ...