Communication between oocytes and granulosa cells is essential for oocyte formation, dormancy, reawakening, and maturation. Researchers have demonstrated that a protein complex called the exocyst ...

Declining female fertility is a health issue that has received broad global attention. Oocyte quality is the key limiting factor of female fertility, and factors affecting oocyte quality involve the ...

One characteristic of oocyte development and physiology that has been a mystery for 60 years is the highly present cytoplasmic lattices within the cytoplasm of mammalian oocytes. These were initially ...

Mechanistic model for MTOC maturation in GV oocytes. The MTOC (grey) activates near the oocyte cortex, which requires recruitment of CKAP5 and TACC3. After activation, MTOC migrates to the nuclear ...

Oocytes are immature egg cells that develop in almost all female mammals before birth. The propagation of future generations depends on this finite reserve of cells surviving for many years without ...