The catalytic hydration of nitriles to amides represents an essential transformation in organic chemistry, offering an atom-economical pathway to synthesise amides that find applications in ...
A pair of copper catalysts can create chiral amides in a new, light-driven process, offering a useful alternative to the standard method for making these staples of medicinal chemistry (Nature 2021, ...
Even though amide bonds are everywhere—they hold proteins together and are essential components in many drugs—forging this molecular motif in a reaction flask can be challenging. For example, making ...
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