In a pair of cross-appeals from the International Trade Commission, the Federal Circuit affirmed the Commission’s ruling that one of CJ CheilJedang Corp.’s engineered bacterial strains infringed ...
A significant portion of modern endocrine research involves Growth Hormone Secretagogues (GHS). These peptides are designed ...
A new mass spectrometry strategy makes it easier to sequence venom peptides, a diverse set of disulfide-rich natural products that are difficult to characterize. For example, the approximately 500 ...
Scientists have developed a way of finding optimal peptide sequences: using a machine-learning algorithm as a collaborator. The algorithm analyzes experimental data and offers suggestions on the next ...
With the “improper Markush grouping” rejection, U.S. patent examiners may reject claims reciting various alternative polynucleotide or polypeptide sequences. However, there is no per se rule that ...
Human α-lactalbumin (α-LA) is a four disulfide-bonded protein that adopts partially structured conformations under a variety of mildly denaturing conditions. At low pH, the protein is denatured but ...
Barcoding technologies using the high information content encoded in oligonucleotide sequences have aided various applications in biotechnology, especially when paired with next-generation DNA ...
Protein production (translation) is a complex process involving machinery called ribosomes. How do cells counter ribosomal destabilization leading to premature termination of translation? Scientists ...
The World Health Organization estimates that antibiotic resistant infections kill more than a million people worldwide every year, so many researchers are actively looking for new ways to combat it.
Scientists and engineers have long been interested in synthesizing peptides — chains of amino acids responsible for conducting many functions within cells — to both mimic nature and to perform new ...