Oocyte maturation and follicular development are fundamental processes that underpin female fertility. These processes involve the transformation of primordial follicles into a cohort of mature, ...

Recent advances in cellular biology have underscored the central role of the actin cytoskeleton in the regulation of oocyte maturation and fertilisation. Actin filament rearrangements not only ...

Professor Rong LI (left) and Dr WANG Haiyang (right) together with their team from the Mechanobiology Institute at the National University of Singapore (NUS) and the NUS Bia-Echo Asia Centre for ...

Mechanistic model for MTOC maturation in GV oocytes. The MTOC (grey) activates near the oocyte cortex, which requires recruitment of CKAP5 and TACC3. After activation, MTOC migrates to the nuclear ...

The accumulation of misfolded or damaged proteins in long-lived, non-dividing cells like neurons are linked to neurodegenerative diseases like Alzheimer's. A study now finds that the build-up of these ...

Nutritional status regulates energetically costly functions like reproduction. 1 Fat tissue serves as both an energy reserve and a metabolic sensor. This sensor operates through a series of ...