Pancreatic cancer is notoriously hard to treat, often resisting therapies that target its most common mutations. Researchers ...

The MYC oncogene family plays an important role in neoplastic disease, and has been extensively studied over decades. Evidence showing the N-terminal and C-terminal regions of MYC can function as a ...

Novel Treatment Targets in Sarcoma: More Than Just the GIST MYC has proven to be a highly potent oncoprotein when it is overexpressed, but is also a pleiotropic transcription factor essential for ...

In healthy cells, the protein MYC helps guide the process of transcription, in which genetic information is converted from DNA into RNA and, eventually, into proteins. However, the shapeless protein ...

Sperm – in theory, you only need one good one to get the job done. Nevertheless, the average pair of human testicles is estimated to crank out about a trillion of these little cells over a lifetime, ...

Researchers have developed a peptide that targets a previously ‘undruggable’ protein implicated in more than 75% of human cancers and found that it slowed the proliferation of brain cancer cells in ...

Clinical and Molecular Characterization of POLE Mutations as Predictive Biomarkers of Response to Immune Checkpoint Inhibitors in Advanced Cancers Urinary 3MT levels and prognosis were investigated in ...

Meet MYC, the shapeless protein responsible for making the majority of human cancer cases worse. UC Riverside researchers have found a way to rein it in, offering hope for a new era of treatments. In ...