An international research team reveals new molecular mechanisms associated with pathogenic mutations in the protein ...

Scientists have long known that inherited neurodegenerative disorders, including Alzheimer's, Parkinson's or motor neuron ...

Unstable proteins are the main drivers of many different heritable diseases, according to a new study, including genetic disorders responsible for the formation of cataracts, and different types of ...

Most mutations that cause disease by swapping one amino acid out for another do so by making the protein less stable, according to a major study of human protein variants that was published in Nature ...

Parkinson's disease (PD) is a debilitating and progressive neurodegenerative disorder caused by the loss of ...

Boffins in Manchester have been studying the gene mutations of fruit flies to solve the riddle of what causes diseases like ...

A study by University of Manchester scientists using fruit flies as model has identified a mechanism which can explain ...

OCTOBER 10, 2024, NEW YORK – A Ludwig Cancer Research study has punctured a longstanding assumption about the source of the most common type of DNA mutation seen in the genome—one that contributes to ...

Using the gene scissors CRISPR and stem cells, researchers at Stockholm University and the UK Dementia Research Institute (UK DRI) at King's College London have managed to identify a common ...

Sickle cell disease is a hereditary condition, which means a person inherits it from their biological parents. The condition occurs when a person inherits two copies of the hemoglobin beta (HBB) gene ...

Francesco Crea is currently funded by a Prostate Cancer UK grant to develop epigenetic cancer therapies. He has also received research funding from Belgian Volition to test cancer biomarkers. Though ...