High-performance liquid chromatography (HPLC) or ultra-high-performance liquid chromatography (UHPLC) serves as the front end of the analysis, reducing sample complexity before mass detection.

When it comes to providing better care, having analytical techniques that can provide high specificity and greater sensitivity all while increasing the laboratories capabilities is essential.

Dr. Joseph Lackey, Technical Manager at LGC Standards, provides an in-depth look at how calibration strategy selection in ...

Biomarkers play an important role in drug development and help in the identification of disease-causing proteins found in blood, urine, body fluids, and tissue samples. The combination of liquid ...

This is the final article in this series discussing HPLC oligonucleotide separations. This article will discuss LC/MS analysis of failure sequences, phosphorothioate modified siRNAs, CpG methylated ...

What will you learn on this course? This is a perfect introduction for absolute beginners to liquid chromatography and LC-MS. The course will cover the what, how, why, where and when of LC & LC-MS.

LC-MS/MS has been increasingly adopted by clinical laboratories due to the potential it has for increased sensitivity and specificity over more commonly used analytical techniques. However, ...

New users of the LC/MS laboratory and Sample Preparation Lab are required to engage in hands-on orientation to facility operations (e.g., laboratory access, scheduling, general use of equipment, ...

LC-MS is used to analyse pharmaceuticals across a variety of stages in their discovery and development. These stages include drug discovery, metabolism studies (in vitro and in vivo), and ...