Endotoxin refers to a component of the outer cell membrane of Gram-negative bacteria called lipopolysaccharide (LPS). LPS is the biologically active portion of naturally occurring endotoxin complexes.

Endotoxin testing is critical in industries such as biopharmaceuticals and medical devices to ensure product safety and reliability. Endotoxins, which are lipopolysaccharides (LPS) found in ...

Endotoxins, primarily lipopolysaccharides (LPS), are components of the outer membrane and cell wall of gram-negative bacteria ...

Bacteria can be found everywhere—even sometimes in clean rooms. That’s a problem for manufacturers of drugs and medical devices that are injected or implanted. Even if manufacturers can remove the ...

Surf on a beach at sunset features a horseshoe crab upside down in the water and several others nearby. Regulatory changes may make the pharmaceutical industry less reliant on horseshoe crabs for ...

Now Niederweis and colleagues at the University of Alabama at Birmingham describe the mechanism of secretion and trafficking of that toxin, TNT, which is the major cytotoxicity factor for the pathogen ...