A Northwestern Medicine study has revealed a previously unknown connection between two fundamental cellular processes, ...
CTCF is widely recognized for its essential role in mediating chromatin loops to regulate gene expression, particularly by modulating enhancer-promoter (EP) interactions. However, acute depletion of ...
Dr. Yasuhiro Arimura studies chromatin, the mixture of DNA and DNA-packaging proteins. Chromatin is “marked” with numerous chemical or structural cues that enable cells to organize DNA and manage how ...
DNA inside human cells is not free-floating. Instead, it is tightly wrapped around small protein units forming a long chain, with DNA looping around each unit before moving on to the next. This ...
EpiCypher® has unveiled its CUTANA® Fiber-seq Kit, designed to make cutting-edge single-molecule chromatin mapping accessible ...
10don MSN
How major nuclear protein complexes control specialized gene regulation in cancer and beyond
Precision and timing of gene expression is essential for normal biological functions and, when disrupted, can lead to many ...
This Brush Up is sponsored by Cayman Chemical. Learn more about chemical inhibitors of histone modification. Histone modification affects how tightly DNA wraps around histone proteins, yielding ...
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