Using ribosome engineering (RE), researchers from Shinshu University introduced mutations affecting the protein synthesis ...
A newly developed luciferase-based reporter can detect problems in protein translocation and disulfide bond formation in the endoplasmic reticulum (ER). Inspired by natural mechanisms found in ...
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Two isoforms of a cellular energy sensor play distinct, opposing roles in Alzheimer's disease
A comprehensive mini-review published today after peer review in Brain Medicine by Dr. Tao Ma and colleagues at Wake Forest ...
The enzyme E3 ligase plays a key role here by acting as a “broker” that mediates the labeling of the proteins to be degraded. A research team at Goethe University Frankfurt has now made the first ...
A newly identified enzyme appears to control tau production, brain inflammation, and aging. Researchers at the University of ...
Researchers have identified OTULIN, an immune-regulating enzyme, as a key trigger of tau buildup in the brain. When OTULIN ...
Key market opportunities in the global competent cells market include rising demands in genetic engineering and synthetic ...
Researchers say discoveries could expand the CRISPR toolbox and lead to more efficient, rapid diagnostic tools for detecting COVID-19, influenza, and RSV.
The FDA approval of denileukin diftitox (Lymphir) marked a significant shift in this paradigm. As a first-in-class immunotoxin, it employs a dual-action mechanism: directly targeting interleukin-2 (IL ...
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