Combining proteasome inhibitors with autophagy inhibitors disrupts acute myeloid leukemia (AML) cells' proteostasis, enhancing treatment efficacy and inducing programmed cell death. The novel therapy ...
SAN DIEGO — Allogeneic stem cell transplant is associated with a significant survival benefit in patients with NPM1-mutated acute myeloid leukemia (AML) who are in their first complete remission and ...
Kura Oncology (KURA) is in good shape with respect to its pipeline in terms of the development of its lead drug, ziftomenib, for the treatment of patients with relapsed/refractory NPM1-mutated Acute ...
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